Quinine

PubChem Notes:

Quinine An alkaloid derived from the bark of the cinchona tree. It is used as an antimalarial drug, and is the active ingredient in extracts of the cinchona that have been used for that purpose since before 1633. Quinine is also a mild antipyretic and analgesic and has been used in common cold preparations for that purpose. It was used commonly and as a bitter and flavoring agent, and is still useful for the treatment of babesiosis. Quinine is also useful in some muscular disorders, especially nocturnal leg cramps and myotonia congenita, because of its direct effects on muscle membrane and sodium channels. The mechanisms of its antimalarial effects are not well understood.

Quinine - definition from Biology-Online.org

[(Science: drug) An alkaloid isolated from cinchona bark. Used as an antimalarial. It is believed to act by raising the pH of endocytotic vesicles and inhibiting internal membrane fusion processes. A bitter alkaloid extracted from chinchona bark; used in malaria therapy.A type of drug extracted from the bark of the cinchona tree which has medicinal value.

Molecular Formula: C20H24N2O2


InChI: InChI=1/C20H24N2O2/c1-3-13-12-22-9-7-14(13)10-19(22)20(23)16-6-8-21-18-5-4-15(24-2)11-17(16)18/h3-6,8,11,13-14,19-20,23H,1,7,9-10,12H2,2H3/t13-,14u,19-,20+/m0/s1

InChIKey: InChIKey=LOUPRKONTZGTKE-ZYIFOKHMBC
SMILES: COC1=CC2=C(C=CN=C2C=C1)C(C3CC4CCN3CC4C=C)O

Names:
    CCRIS 5755
    Chinine
    Chinin [German]
    Quinine anhydrous
    Quinine [BAN]
    Quinine
    (S)-[(5S,7S)-5-ethenyl-1-azabicyclo[2.2.2]oct-7-yl]-(6-methoxyquinolin-4-yl)methanol
    (-)-Quinine
    (8S,9R)-Quinine
    6'-Methoxycinchonan-9-ol
    6-Methoxycinchonine

Registries:
    PubChem CID 8549
    PubChem ID 151706