quinine sulfate

Quinine An alkaloid derived from the bark of the cinchona tree. It is used as an antimalarial drug, and is the active ingredient in extracts of the cinchona that have been used for that purpose since before 1633. Quinine is also a mild antipyretic and analgesic and has been used in common cold preparations for that purpose. It was used commonly and as a bitter and flavoring agent, and is still useful for the treatment of babesiosis. Quinine is also useful in some muscular disorders, especially nocturnal leg cramps and myotonia congenita, because of its direct effects on muscle membrane and sodium channels. The mechanisms of its antimalarial effects are not well understood.

Molecular Formula: C₄₀H₅₄N₄O₁₀S

InChI: InChI=1/2C20H24N2O2.H2O4S.2H2O/c2*1-3-13-12-22-9-7-14(13)10-19(22)20(23)16-6-8-21-18-5-4-15(24-2)11-17(16)18;1-5(2,3)4;;/h2*3-6,8,11,13-14,19-20,23H,1,7,9-10,12H2,2H3;(H2,1,2,3,4);2*1H2/t2*13-,14u,19-,20+;;;/m00.../s1/f/h;;1-2H;;

InChIKey: InChIKey=ZHNFLHYOFXQIOW-NCRJODEQDI
SMILES: COC1=CC2=C(C=CN=C2C=C1)C(C3CC4CCN3CC4C=C)O.COC1=CC2=C(C=CN=C2C=C1)C(C3CC4CCN3CC4C=C)O.O.O.OS(=O)(=O)O

Names:
    DRG-0052
    FEMA No. 2977
    Quinamm
    Quinine sulfate dihydrate [USAN:JAN]
    QUININE SULFATE DIHYDRATE
    Quinine sulfate (2:1) (salt) dihydrate
    Quinine Sulfate [USAN:JAN]
    quinine sulfate
    Quinine, sulfate (2:1), dihydrate
    (S)-[(5S,7S)-5-ethenyl-1-azabicyclo[2.2.2]oct-7-yl]-(6-methoxyquinolin-4-yl)methanol; sulfuric acid; dihydrate
    6'-Methoxycinchonan-9-ol sulfate dihydrate, (8alpha,9R)-, (2:1) (salt)

Registries:
    PubChem CID 61367
    PubChem ID 197631