Gentamicin sulfate

Gentamicins A complex of three different closely related aminoglycoside sulfates, Gentamicins C1, C2, and C1(subA), obtained from Micromonospora purpurea and related species. They are broad-spectrum antibiotics, but may cause ear and kidney damage. They act to inhibit protein synthesis (TRANSLATION (GENETICS)).

Molecular Formula: C₂₁H₄₅N₅O₁₁S

InChI: InChI=1/C21H43N5O7.H2O4S/c1-9(25-3)13-6-5-10(22)19(31-13)32-16-11(23)7-12(24)17(14(16)27)33-20-15(28)18(26-4)21(2,29)8-30-20;1-5(2,3)4/h9-20,25-29H,5-8,22-24H2,1-4H3;(H2,1,2,3,4)/t9u,10-,11+,12-,13+,14+,15-,16?,17+,18-,19-,20?,21+;/m1./s1/f/h;1-2H

InChIKey: InChIKey=NWQISSNHRDDWRM-CPDUMUCLDI
SMILES: CC(C1CCC(C(O1)OC2C(CC(C(C2O)OC3C(C(C(CO3)(C)O)NC)O)N)N)N)NC.OS(=O)(=O)O

Names:
    Gentamicin sulfate
    (3R,4R,5S)-2-[(1S,2R,4S,6R)-4,6-diamino-3-[(2R,3R,6S)-3-amino-6-(1-methylaminoethyl)oxan-2-yl]oxy-2-hydroxy-cyclohexyl]oxy-5-methyl-4-methylamino-oxane-3,5-diol; sulfuric acid

Registries:
    PubChem CID 5702059
    PubChem ID 8149357