galanthamine

Galantamine A benzazepine derived from norbelladine. It is found in GALANTHUS and other AMARYLLIDACEAE. It is a cholinesterase inhibitor that has been used to reverse the muscular effects of GALLAMINE TRIETHIODIDE and TUBOCURARINE and has been studied as a treatment for ALZHEIMER DISEASE and other central nervous system disorders.

[1. An alkaloid derived from Caucasian snowdrops (a white flower of early spring) Galanthus woronowii (family Amaryllidaceae); from Narcissus spp. An alkaloid with anticholinesterase properties; enjoys use in Eastern Europe.

Molecular Formula: C₁₇H₂₁NO₃

InChI: InChI=1/C17H21NO3/c1-18-8-7-17-6-5-12(19)9-14(17)21-16-13(20-2)4-3-11(10-18)15(16)17/h3-6,12,14,19H,7-10H2,1-2H3/t12-,14-,17-/m0/s1

InChIKey: InChIKey=ASUTZQLVASHGKV-JDFRZJQEBY
SMILES: [H][C@]12C[C@@H](O)C=C[C@]13CCN(C)Cc4ccc(OC)c(O2)c34

CAS number 357-70-0

Names:
    C08526
    Galantamine
    galanthamine
    Galanthamine
    galanthamine
    (-)-GALANTHAMINE
    357-70-0

Registries:
    PubChem CID 9651
    Beilstein =93736
    CAS 357-70-0 (from NIST)
    ChEBI 5264
    chemPDB GNT
    Kegg C08526
    PubChem ID 10719