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Debrisoquin An adrenergic neuron-blocking drug similar in effects to GUANETHIDINE. It is also noteworthy in being a substrate for a polymorphic cytochrome P-450 enzyme. Persons with certain isoforms of this enzyme are unable to properly metabolize this and many other clinically important drugs. They are commonly referred to as having a debrisoquin 4-hydroxylase polymorphism.
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Molecular Formula:
C20H28N6O4S
InChI: InChI=1/2C10H13N3.H2O4S/c2*11-10(12)13-6-5-8-3-1-2-4-9(8)7-13;1-5(2,3)4/h2*1-4H,5-7H2,(H3,11,12);(H2,1,2,3,4)/f/h2*11H,12H2;1-2H/b2*11-10+;
InChIKey: InChIKey=CAYGYVYWRIHZCQ-HQDRXKAVDP
SMILES: C1CN(CC2=CC=CC=C21)C(=N)N.C1CN(CC2=CC=CC=C21)C(=N)N.OS(=O)(=O)O
Names:
Debrisoquine sulphate
Debrisoquin hemisulfate
Debrisoquin sulfate [USAN]
DEBRISOQUIN SULFATE
Declinax
EINECS 209-472-4
Equitonil
Isocaramidine sulfate
Pasiron-T
Tendor
3,4-dihydro-1H-isoquinoline-2-carboximidamide; sulfuric acid
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Registries:
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PubChem CID 11391
PubChem ID 154695
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