THIORPHAN

Thiorphan A potent inhibitor of membrane metalloendopeptidase (ENKEPHALINASE). Thiorphan potentiates morphine-induced ANALGESIA and attenuates naloxone-precipitated withdrawal symptoms.

Molecular Formula: C₁₂H₁₅NO₃S

InChI: InChI=1/C12H15NO3S/c14-11(15)7-13-12(16)10(8-17)6-9-4-2-1-3-5-9/h1-5,10,17H,6-8H2,(H,13,16)(H,14,15)/f/h13-14H

InChIKey: InChIKey=LJJKNPQAGWVLDQ-KGCNKATMCP
SMILES: C1=CC=C(C=C1)CC(CS)C(=O)NCC(=O)O

Names:
    Prestwick_694
    THIORPHAN
    2-[(2-benzyl-3-sulfanyl-propanoyl)amino]acetic acid
    76721-89-6

Registries:
    PubChem CID 3132
    PubChem ID 10321651