TUFTSIN

Tuftsin N(2)-((1-(N(2)-L-Threonyl)-L-lysyl)-L-prolyl)-L-arginine. A tetrapeptide produced in the spleen by enzymatic cleavage of a leukophilic gamma-globulin. It stimulates the phagocytic activity of blood polymorphonuclear leukocytes and neutrophils in particular. The peptide is located in the Fd fragment of the gamma-globulin molecule.

Molecular Formula: C₂₁H₄₀N₈O₆

InChI: InChI=1/C21H40N8O6/c1-12(30)16(23)18(32)27-13(6-2-3-9-22)19(33)29-11-5-8-15(29)17(31)28-14(20(34)35)7-4-10-26-21(24)25/h12-16,30H,2-11,22-23H2,1H3,(H,27,32)(H,28,31)(H,34,35)(H4,24,25,26)/f/h27-28,34H,24-25H2

InChIKey: InChIKey=IESDGNYHXIOKRW-FSOFNBMKCO
SMILES: CC(C(C(=O)NC(CCCCN)C(=O)N1CCCC1C(=O)NC(CCCN=C(N)N)C(=O)O)N)O

Names:
    L-Arginine, N2-(1-(N2-L-threonyl-L-lysyl)-L-prolyl)-
    TUFTSIN
    2-[[1-[6-amino-2-[(2-amino-3-hydroxy-butanoyl)amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-5-(diaminomethylideneamino)pentanoic acid
    37019-52-6
    38642-14-7
    9063-57-4

Registries:
    PubChem CID 24780
    PubChem ID 167564