Molindone hydrochloride

Molindone An indole derivative effective in schizophrenia and other psychoses and possibly useful in the treatment of the aggressive type of undersocialized conduct disorder. Molindone has much lower affinity for D2 receptors than most antipsychotic agents and has a relatively low affinity for D1 receptors. It has only low to moderate affinity for cholinergic and alpha-adrenergic receptors. Some electrophysiologic data from animals indicate that molindone has certain characteristics that resemble those of CLOZAPINE. (From AMA Drug Evaluations Annual, 1994, p283)

Molecular Formula: C₁₆H₂₅ClN₂O₂

InChI: InChI=1/C16H24N2O2.ClH/c1-3-13-11(2)17-14-5-4-12(16(19)15(13)14)10-18-6-8-20-9-7-18;/h12,17H,3-10H2,1-2H3;1H/fC16H25N2O2.Cl/h18H;1h/q+1;-1

InChIKey: InChIKey=GQWNECFJGBQMBO-DOUWSCLKCA
SMILES: CCC1=C(NC2=C1C(=O)C(CC2)C[NH+]3CCOCC3)C.[Cl-]

Names:
    EN 1733 A
    Indol-4(5H)-one, 3-ethyl-6,7-dihydro-2-methyl-5-(morpholinomethyl)-, monohydrochloride
    INDOL-4(5H)-ONE, 3-ETHYL-6,7-DIHYDRO-2-METHYL-5-(MORPHOLINOMETHYL)-, MONOHYDROCH
    Lidone
    Moban
    Molindone hydrochloride [USAN]
    Molindone hydrochloride
    15622-65-8
    3-ethyl-2-methyl-5-(1-oxa-4-azoniacyclohex-4-ylmethyl)-1,5,6,7-tetrahydroindol-4-one chloride
    3-Ethyl-6,7-dihydro-2-methyl-5-morpholinomethylindol-4(5H)-one hydrochloride
    3-Ethyl-6,7-dihydro-2-methyl-5-(morpholinomethyl)indol-4(5H)-one monohydrochloride

Registries:
    PubChem CID 27421
    PubChem ID 170014