Etacrynic Acid

Ethacrynic Acid A compound that inhibits symport of sodium, potassium, and chloride primarily in the ascending limb of Henle, but also in the proximal and distal tubules. This pharmacological action results in excretion of these ions, increased urinary output, and reduction in extracellular fluid. This compound has been classified as a loop or high ceiling diuretic.

Molecular Formula: C₁₄H₁₆N₂O₄

InChI: InChI=1/C14H16N2O4/c1-9(17)7-13(19)15-11-5-3-4-6-12(11)16-14(20)8-10(2)18/h3-6H,7-8H2,1-2H3,(H,15,19)(H,16,20)/f/h15-16H

InChIKey: InChIKey=ISYMWANHPZRQAP-LUXCBXFACC
SMILES: CC(=O)CC(=O)NC1=CC=CC=C1NC(=O)CC(=O)C

Names:
    Etacrynic Acid
    NSC8791
    3-oxo-N-[2-(3-oxobutanoylamino)phenyl]butanamide
    5422-28-6

Registries:
    PubChem CID 222525
    PubChem ID 74407