Tienamycin

PubChem Notes:

Imipenem Semisynthetic thienamycin that has a wide spectrum of antibacterial activity against gram-negative and gram-positive aerobic and anaerobic bacteria, including many multiresistant strains. It is stable to beta-lactamases. Clinical studies have demonstrated high efficacy in the treatment of infections of various body systems. Its effectiveness is enhanced when it is administered in combination with CILASTATIN, a renal dipeptidase inhibitor.

Molecular Formula: C12H17N3O4S


InChI: InChI=1/C12H17N3O4S/c1-6(16)9-7-4-8(20-3-2-14-5-13)10(12(18)19)15(7)11(9)17/h5-7,9,16H,2-4H2,1H3,(H2,13,14)(H,18,19)/t6-,7+,9+/m0/s1/f/h18H,13H2/b14-5+

InChIKey: InChIKey=ZSKVGTPCRGIANV-QCANODTIDQ
SMILES: CC(C1C2CC(=C(N2C1=O)C(=O)O)SCCN=CN)O

Names:
    EINECS 264-734-5
    Imipenemum [Latin]
    Imipenem anhydrous
    imipenem
    MK 0787
    MK-787
    N-Formimidoylthienamycin
    Tienamycin
    (5R,6S)-3-((2-(Formimidoylamino)ethyl)thio)-6-((R)-1-hydroxyethyl)-7-oxo-1-azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid
    (5R,6S)-3-[2-(aminomethylideneamino)ethylsulfanyl]-6-(1-hydroxyethyl)-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
    (5R,6S)-6-((R)-1-Hydroxyethyl)-3-(2-(iminomethylamino)ethylthio)-7-oxo-1-azabicyclo(3.2.0)hept-2-ene-2-carbonsaeure

Registries:
    PubChem CID 47317
    PubChem ID 186607