norepinephrine

Norepinephrine Precursor of epinephrine that is secreted by the adrenal medulla and is a widespread central and autonomic neurotransmitter. Norepinephrine is the principal transmitter of most postganglionic sympathetic fibers and of the diffuse projection system in the brain arising from the locus ceruleus. It is also found in plants and is used pharmacologically as a sympathomimetic.

[1. A catecholamine hormone the natural form of which is d, although the l form has some activity; the base is considered to be the postganglionic adrenergic mediator, acting on α and β receptors; it is stored in chromaffin granules in the adrenal medulla in much smaller amounts than epinephrine and secreted in response to hypotension and physical stress; in contrast to epinephrine it has little effect on bronchial smooth muscle, metabolic processes, and cardiac output, but has strong vasoconstrictive effects and is used pharmacologically as a vasopressor, primarily as the bitartrate salt.

Molecular Formula: C₈H₁₁NO₃

InChI: InChI=1/C8H11NO3/c9-4-8(12)5-1-2-6(10)7(11)3-5/h1-3,8,10-12H,4,9H2

InChIKey: InChIKey=SFLSHLFXELFNJZ-UHFFFAOYAU
SMILES: NCC(O)c1ccc(O)c(O)c1

CAS number 138-65-8

Names:
    CHEBI:33569
    noradrenaline
    norepinephrine
    138-65-8
    4-(2-amino-1-hydroxyethyl)benzene-1,2-diol
    4-(2-amino-1-hydroxy-ethyl)benzene-1,2-diol

Registries:
    PubChem CID 951
    Beilstein =2210994
    CAS 138-65-8 (from NIST)
    ChEBI 33569
    Gmelin 863925
    PubChem ID 10318916