clavulanic acid

Clavulanic acid - definition from

[(Science: chemical) clavulanic acid (c8h9o5n) and its salts and esters. The acid is a suicide inhibitor of bacterial beta-lactamase enzymes from streptomyces clavuligerus. Administered alone, it has only weak antibacterial activity against most organisms, but given in combination with beta-lactam antibiotics prevents antibiotic inactivation by microbial lactamase. Pharmacological action: antibiotics, lactam, enzyme inhibitors. chemical name: 4-Oxa-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 3-(2-hydroxyethylidene)-7-oxo-, (2R-(2alpha,3Z,5alpha))

MediLexicon clavulanic acid - Medical Dictionary Definition for Term 'clavulanic acid'

[1. A β-lactam structurally related to the penicillins that inactivate β-lactamase enzymes in penicillin-resistant organisms; usually used in combination with penicillins to enhance and broaden the spectrum of the penicillins.

InChI: InChI=1/C8H9NO5/c10-2-1-4-7(8(12)13)9-5(11)3-6(9)14-4/h1,6-7,10H,2-3H2,(H,12,13)/b4-1-/t6-,7-/m1/s1

SMILES: [H][C@@]12CC(=O)N1[C@@H](C(O)=O)C(\O2)=C\CO

    Clavulanic acid
    clavulanic acid

    PubChem CID 5280980
    ChEBI 3736
    Kegg C06662
    PubChem ID 8887