glycyrrhizinic acid

Glycyrrhizic acid - definition from Biology-Online.org

[(Science: chemical, drug) a widely used anti-inflammatory agent isolated from the licorice root. It is metabolised to glycyrrhetic acid, which inhibits 11 beta-hydroxysteroid dehydrogenase and other enzymes involved in the metabolism of corticosteroids. Therefore, glycyrrhizic acid, which is the main and sweet component of licorice, has been investigated for its ability to cause hypermineralocorticoidism with sodium retention and potassium loss, oedema, increased blood pressure, as well as depression of the renin-angiotensin-aldosterone system. Pharmacological action: anti-infective agents, non-steroidal anti-inflammatory agents, antifungal agents, antiviral agents. chemical name: alpha-D-glucopyranosiduronic acid, (3 beta,20 beta)-20-carboxy-11-oxo-30-norolean-12-en-3-yl 2-O-beta-D-glucopyranuronosyl-


InChI: InChI=1/C42H62O16/c1-37(2)21-8-11-42(7)31(20(43)16-18-19-17-39(4,36(53)54)13-12-38(19,3)14-15-41(18,42)6)40(21,5)10-9-22(37)55-35-30(26(47)25(46)29(57-35)33(51)52)58-34-27(48)23(44)24(45)28(56-34)32(49)50/h16,19,21-31,34-35,44-48H,8-15,17H2,1-7H3,(H,49,50)(H,51,52)(H,53,54)/t19-,21-,22-,23-,24-,25-,26-,27+,28-,29-,30+,31+,34-,35-,38+,39-,40-,41+,42+/m0/s1

InChIKey: InChIKey=LPLVUJXQOOQHMX-QWBHMCJMBD
SMILES: [H][C@@]12C[C@](C)(CC[C@]1(C)CC[C@]3(C)C2=CC(=O)[C@]4([H])[C@@]5(C)CC[C@H](O[C@H]6O[C@@H]([C@@H](O)[C@H](O)[C@H]6O[C@@H]7O[C@@H]([C@@H](O)[C@H](O)[C@H]7O)C(O)=O)C(O)=O)C(C)(C)[C@]5([H])CC[C@@]34C)C(O)=O

CAS number 1405-86-3

Names:
    Glycyrrhizic acid
    Glycyrrhizinate
    Glycyrrhizin
    glycyrrhizinic acid
    (3β,20β)-20-carboxy-11-oxo-30-norolean-12-en-3-yl-2-O-;=_ӱ

Registries:
    PubChem CID 3495
    Beilstein =77922
    CAS 1405-86-3 (from NIST)
    ChEBI 15939
    Kegg C02284
    PubChem ID 5341