DOCA

Desoxycorticosterone 21-Hydroxypregn-4-ene-3,20-dione. Mineralocorticoid. Desoxycorticosterone acetate (DOCA) is used as replacement therapy in Addison's Disease.

[deoxycorticosterone 11-Deoxycorticosterone; 21-hydroxypregn-4-ene-3,20-dione;an adrenocortical steroid, principally a biosynthetic precursor of corticosterone and possibly aldosterone, that rarely appears in adrenocortical secretions; a potent mineralocorticoid with no appreciable glucocorticoid activity. Synonym: 21-hydroxyprogesterone, cortexone, deoxycortone, desoxycortone. Deoxycorticosterone acetate, desoxycorticosterone acetate;acetate salt used for intramuscular injection for replacement therapy of the adrenocortical steroid. Deoxycorticosterone pivalate, desoxycorticosterone pivalate;pivalate salt of the steroid.

[1. A steroid derived from the adrenal cortex with strong mineralocorticoid activity.

Molecular Formula: C₂₁H₃₀O₃

InChI: InChI=1/C21H30O3/c1-20-9-7-14(23)11-13(20)3-4-15-16-5-6-18(19(24)12-22)21(16,2)10-8-17(15)20/h11,15-18,22H,3-10,12H2,1-2H3

InChIKey: InChIKey=ZESRJSPZRDMNHY-UHFFFAOYAU
SMILES: CC12CCC3C(C1CCC2C(=O)CO)CCC4=CC(=O)CCC34C

Names:
    Cortexone
    Deoxycorticosterone
    Deoxycortone
    desoxycorticosterone
    Desoxycortone
    DOCA
    Reichstein's substance Q
    11-Deoxycorticosterone
    11-Desoxycorticosterone
    17-(2-hydroxyacetyl)-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one
    21-Hydroxyprogesterone

Registries:
    PubChem CID 223578
    PubChem ID 76337