Nomifensine

Nomifensine An isoquinoline derivative that prevents dopamine reuptake into synaptosomes. The maleate was formerly used in the treatment of depression. It was withdrawn worldwide in 1986 due to the risk of acute hemolytic anemia with intravascular hemolysis resulting from its use. In some cases, renal failure also developed. (From Martindale, The Extra Pharmacopoeia, 30th ed, p266)

Molecular Formula: C₁₆H₁₈N₂

InChI: InChI=1/C16H18N2/c1-18-10-14(12-6-3-2-4-7-12)13-8-5-9-16(17)15(13)11-18/h2-9,14H,10-11,17H2,1H3

InChIKey: InChIKey=XXPANQJNYNUNES-UHFFFAOYAL
SMILES: CN1CC(C2=C(C1)C(=CC=C2)N)C3=CC=CC=C3

Names:
    Isoquinoline, 1,2,3,4-tetrahydro-8-amino-2-methyl-4-phenyl-
    Linamiphen
    Nomifensina [INN-Spanish]
    nomifensin
    Nomifensine
    Nomifensinum [INN-Latin]
    (+-)-Nomifensine
    (+-)-Nomifensin
    2-methyl-4-phenyl-3,4-dihydro-1H-isoquinolin-8-amine
    8-Amino-1,2,3,4-tetrahydro-2-methyl-4-phenylisochinolin
    8-Amino-2-methyl-4-phenyl-1,2,3,4-tetrahydroisoquinoline

Registries:
    PubChem CID 4528
    PubChem ID 174438