Topotecan monohydrochloride

Topotecan An antineoplastic agent used to treat ovarian cancer. It works by inhibiting DNA TOPOISOMERASES, TYPE I.

Molecular Formula: C₂₃H₂₄ClN₃O₅

InChI: InChI=1/C23H23N3O5.ClH/c1-4-23(30)16-8-18-20-12(9-26(18)21(28)15(16)11-31-22(23)29)7-13-14(10-25(2)3)19(27)6-5-17(13)24-20;/h5-8,27,30H,4,9-11H2,1-3H3;1H/t23-;/m0./s1

InChIKey: InChIKey=DGHHQBMTXTWTJV-BQAIUKQQBZ
SMILES: CCC1(C2=C(COC1=O)C(=O)N3CC4=C(C3=C2)N=C5C=CC(=C(C5=C4)CN(C)C)O)O.Cl

Names:
    DRG-0288
    Hycamptamine hydrochloride
    Hycamtin
    SK&F S-104864-A
    Topotecan hydrochloride [USAN]
    TOPOTECAN HYDROCHLORIDE
    Topotecan monohydrochloride
    (S)-10-((Dimethylamino)methyl)-4-ethyl-4,9-dihydroxy-1H-pyrano(3',4':6,7)indolizino(1,2-b)quinoline-3,14(4H,12H)-dione monohydrochloride
    1H-Pyrano(3',4':6,7)indolizino(1,2-b)quinoline-3,14(4H,12H)-dione, 10-((dimethylamino)methyl)-4-ethyl-4,9-dihydroxy-, monohydrochloride, (S)-
    119413-54-6

Registries:
    PubChem CID 60699
    PubChem ID 196964