VePesid
PubChem Notes:
Etoposide A semisynthetic derivative of PODOPHYLLOTOXIN that exhibits antitumor activity. Etoposide inhibits DNA synthesis by forming a complex with topoisomerase II and DNA. This complex induces breaks in double stranded DNA and prevents repair by topoisomerase II binding. Accumulated breaks in DNA prevent entry into the mitotic phase of cell division, and lead to cell death. Etoposide acts primarily in the G2 and S phases of the cell cycle.
Etoposide - definition from Biology-Online.org
[(Science: drug, oncology) etoposide is a semisynthetic derivative of podophyllotoxin used in the treatment of certain neoplastic diseases. It may be administered either intravenously or orally. side effects: low blood counts and chance of allergic reactions.
Molecular Formula:
C29H32O13
InChI: InChI=1/C29H32O13/c1-11-36-9-20-27(40-11)24(31)25(32)29(41-20)42-26-14-7-17-16(38-10-39-17)6-13(14)21(22-15(26)8-37-28(22)33)12-4-18(34-2)23(30)19(5-12)35-3/h4-7,11,15,20-22,24-27,29-32H,8-10H2,1-3H3/t11-,15+,20-,21-,22+,24-,25-,26-,27-,29+/m1/s1
InChIKey: InChIKey=VJJPUSNTGOMMGY-MRVIYFEKBZ
SMILES: [H][C@]12COC(=O)[C@]1([H])[C@H](C3=CC(OC)=C(O)C(OC)=C3)C4=C(C=C5OCOC5=C4)[C@H]2O[C@@H]6O[C@@H]7CO[C@@H](C)O[C@H]7[C@H](O)[C@H]6O
Names:
EPEG
Etopol
Etopophos
etoposide
Etoposide
etoposide
Etosid
Lastet
NSC-141540
Vepeside
VePesid
VP-16
4'-Demethylepipodophyllotoxin 9-(4,6-O-(R)-ethylidene-beta-D-glucopyranoside)
9-((4,6-O-Ethylidine-beta-D-glucopyranosyl)oxy)-5,8,8a,9-tetrahydro-5-(4-hydroxy-
Registries:
PubChem CID 36462
ChEBI 4911
Kegg C01576
PubChem ID 12013288
PubChem ID 4733
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