PubChem Notes:

Etoposide A semisynthetic derivative of PODOPHYLLOTOXIN that exhibits antitumor activity. Etoposide inhibits DNA synthesis by forming a complex with topoisomerase II and DNA. This complex induces breaks in double stranded DNA and prevents repair by topoisomerase II binding. Accumulated breaks in DNA prevent entry into the mitotic phase of cell division, and lead to cell death. Etoposide acts primarily in the G2 and S phases of the cell cycle.

Etoposide - definition from

[(Science: drug, oncology) etoposide is a semisynthetic derivative of podophyllotoxin used in the treatment of certain neoplastic diseases. It may be administered either intravenously or orally. side effects: low blood counts and chance of allergic reactions.

Molecular Formula: C29H32O13

InChI: InChI=1/C29H32O13/c1-11-36-9-20-27(40-11)24(31)25(32)29(41-20)42-26-14-7-17-16(38-10-39-17)6-13(14)21(22-15(26)8-37-28(22)33)12-4-18(34-2)23(30)19(5-12)35-3/h4-7,11,15,20-22,24-27,29-32H,8-10H2,1-3H3/t11-,15+,20-,21-,22+,24-,25-,26-,27-,29+/m1/s1

SMILES: [H][C@]12COC(=O)[C@]1([H])[C@H](C3=CC(OC)=C(O)C(OC)=C3)C4=C(C=C5OCOC5=C4)[C@H]2O[C@@H]6O[C@@H]7CO[C@@H](C)O[C@H]7[C@H](O)[C@H]6O

    4'-Demethylepipodophyllotoxin 9-(4,6-O-(R)-ethylidene-beta-D-glucopyranoside)

    PubChem CID 36462
    ChEBI 4911
    Kegg C01576
    PubChem ID 12013288
    PubChem ID 4733