Ethacrynic acid sodium

Ethacrynic Acid A compound that inhibits symport of sodium, potassium, and chloride primarily in the ascending limb of Henle, but also in the proximal and distal tubules. This pharmacological action results in excretion of these ions, increased urinary output, and reduction in extracellular fluid. This compound has been classified as a loop or high ceiling diuretic.

Molecular Formula: C₁₃H₁₁Cl₂NaO₄

InChI: InChI=1/C13H12Cl2O4.Na/c1-3-7(2)13(18)8-4-5-9(12(15)11(8)14)19-6-10(16)17;/h4-5H,2-3,6H2,1H3,(H,16,17);/q;+1/p-1/fC13H11Cl2O4.Na/q-1;m

InChIKey: InChIKey=CWCSCNSKBSCYCS-FMKDANTMCN
SMILES: CCC(=C)C(=O)C1=C(C(=C(C=C1)OCC(=O)[O-])Cl)Cl.[Na+]

Names:
    Acetic acid, (2,3-dichloro-4-(2-methylene-1-oxobutyl)phenoxy)-, sodium salt
    Edecrin Sodium
    Ethacrynate Sodium [USAN]
    ETHACRYNATE SODIUM
    ethacrynate
    Ethacrynic acid sodium
    Sodium (2,3-dichloro-4-(2-methylenebutyryl)phenoxy)acetate
    sodium 2-[2,3-dichloro-4-(2-methylidenebutanoyl)phenoxy]acetate
    58-54-8
    6500-81-8

Registries:
    PubChem CID 23003
    PubChem ID 165582