Puromycin dihydrochloride

Puromycin A cinnamamido ADENOSINE found in STREPTOMYCES alboniger. It inhibits protein synthesis by binding to RNA. It is an antineoplastic and antitrypanosomal agent and is used in research as an inhibitor of protein synthesis.

Molecular Formula: C₂₂H₃₁Cl₂N₇O₅

InChI: InChI=1/C22H29N7O5.2ClH/c1-28(2)19-17-20(25-10-24-19)29(11-26-17)22-18(31)16(15(9-30)34-22)27-21(32)14(23)8-12-4-6-13(33-3)7-5-12;;/h4-7,10-11,14-16,18,22,30-31H,8-9,23H2,1-3H3,(H,27,32);2*1H/t14?,15-,16+,18?,22-;;/m1../s1/f/h27H;;

InChIKey: InChIKey=MKSVFGKWZLUTTO-ZJXCHSIKDO
SMILES: CN(C)C1=NC=NC2=C1N=CN2C3C(C(C(O3)CO)NC(=O)C(CC4=CC=C(C=C4)OC)N)O.Cl.Cl

Names:
    Prestwick_627
    Puromycin dihydrochloride
    2-amino-N-[(2R,3R,5R)-5-(6-dimethylaminopurin-9-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl]-3-(4-methoxyphenyl)propanamide dihydrochloride
    58-58-2

Registries:
    PubChem CID 6419988
    PubChem ID 10321593