TSH-releasing hormone

Protirelin A tripeptide hormone that originates in the hypothalamus and stimulates the secretion of thyrotropin from the pituitary gland. In humans, it also acts as a prolactin-releasing factor. It is also a neurotransmitter in the central nervous system.

Molecular Formula: C₁₆H₂₂N₆O₄

InChI: InChI=1/C16H22N6O4/c17-14(24)12-2-1-5-22(12)16(26)11(6-9-7-18-8-19-9)21-15(25)10-3-4-13(23)20-10/h7-8,10-12H,1-6H2,(H2,17,24)(H,18,19)(H,20,23)(H,21,25)/f/h19-21H,17H2

InChIKey: InChIKey=XNSAINXGIQZQOO-DUXAZCAECX
SMILES: C1CC(N(C1)C(=O)C(CC2=CN=CN2)NC(=O)C3CCC(=O)N3)C(=O)N

Names:
    Abbott 38579
    Lopremone
    N-[1-(2-carbamoylpyrrolidin-1-yl)-3-(3H-imidazol-4-yl)-1-oxo-propan-2-yl]-5-oxo-pyrrolidine-2-carboxamide
    protirelin
    Rifathyroin
    Synthetic TRH
    Thypinone
    Thyroid releasing hormone
    Thyroliberin
    TSH-releasing factor
    TSH-releasing hormone

Registries:
    PubChem CID 32281
    PubChem ID 174257