methysergide

Methysergide An ergot derivative that is a congener of LYSERGIC ACID DIETHYLAMIDE. It antagonizes the effects of serotonin in blood vessels and gastrointestinal smooth muscle, but has few of the properties of other ergot alkaloids. Methysergide is used prophylactically in migraine and other vascular headaches and to antagonize serotonin in the carcinoid syndrome.

Molecular Formula: C₂₁H₂₇N₃O₂

InChI: InChI=1/C21H27N3O2/c1-4-15(12-25)22-21(26)14-8-17-16-6-5-7-18-20(16)13(10-23(18)2)9-19(17)24(3)11-14/h5-8,10,14-15,19,25H,4,9,11-12H2,1-3H3,(H,22,26)/t14-,15+,19-/m1/s1/f/h22H

InChIKey: InChIKey=KPJZHOPZRAFDTN-YBSCGTCVDI
SMILES: CCC(CO)NC(=O)C1CN(C2CC3=CN(C4=CC=CC(=C34)C2=C1)C)C

Names:
    Deseril
    Desernil
    Desernyl
    Deseryl
    Methysergid
    methysergide
    Methysergidum [INN-Latin]
    Metisergide [DCIT]
    Metisergido [INN-Spanish]
    1-Methylmethylergonovine

Registries:
    PubChem CID 9681
    PubChem ID 152894