floxuridine

Floxuridine An antineoplastic antimetabolite that is metabolized to fluorouracil when administered by rapid injection; when administered by slow, continuous, intra-arterial infusion, it is converted to floxuridine monophosphate. It has been used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract.

Molecular Formula: C₉H₁₁FN₂O₅

InChI: InChI=1/C9H11FN2O5/c10-4-2-12(9(16)11-8(4)15)7-1-5(14)6(3-13)17-7/h2,5-7,13-14H,1,3H2,(H,11,15,16)/t5-,6-,7?/m1/s1/f/h11H

InChIKey: InChIKey=ODKNJVUHOIMIIZ-OSBZMBFVDL
SMILES: C1C(C(OC1N2C=C(C(=O)NC2=O)F)CO)O

Names:
    floxuridine
    5-fluoro-1-[(4R,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione

Registries:
    PubChem CID 5702211
    PubChem ID 8149885