NICORANDIL

Nicorandil A derivative of the NIACINAMIDE that is structurally combined with an organic nitrate. It is a potassium-channel opener that causes vasodilatation of arterioles and large coronary arteries. Its nitrate-like properties produce venous vasodilation through stimulation of guanylate cyclase.

Molecular Formula: C₈H₉N₃O₄

InChI: InChI=1/C8H9N3O4/c12-8(7-2-1-3-9-6-7)10-4-5-15-11(13)14/h1-3,6H,4-5H2,(H,10,12)/f/h10H

InChIKey: InChIKey=LBHIOVVIQHSOQN-KZFATGLACO
SMILES: C1=CC(=CN=C1)C(=O)NCCO[N+](=O)[O-]

Names:
    BRN 0481451
    EINECS 265-514-1
    Nicorandilum [INN-Latin]
    Nicorandil [USAN:BAN:INN:JAN]
    NICORANDIL
    N-(2-Hydroxyethyl)nicotinamide nitrate
    SG 75
    2-Nicotinamidoethyl nitrate
    2-(Nicotinamido)ethyl nitrat
    2-(pyridine-3-carbonylamino)ethyl nitrate
    3-Pyridinecarboxamide, N-(2-(nitroxy)ethyl)-

Registries:
    PubChem CID 47528
    PubChem ID 186802