cyclophosphamide

Cyclophosphamide Precursor of an alkylating nitrogen mustard antineoplastic and immunosuppressive agent that must be activated in the liver to form the active ALDOPHOSPHAMIDE. It is used in the treatment of lymphomas, leukemias, etc. Its side effect, ALOPECIA, has been used for defleecing sheep. Cyclophosphamide may also cause sterility, birth defects, mutations, and cancer.

Molecular Formula: C₇H₁₅Cl₂N₂O₂P

InChI: InChI=1/C7H15Cl2N2O2P/c8-2-5-11(6-3-9)14(12)10-4-1-7-13-14/h1-7H2,(H,10,12)/f/h10H

InChIKey: InChIKey=CMSMOCZEIVJLDB-KZFATGLACB
SMILES: ClCCN(CCCl)P1(=O)NCCCO1

CAS number 50-18-0

Names:
    Bis(2-chloroethyl)phosphoramide cyclic propanolamide ester
    Cyclophosphamide anhydrous
    cyclophosphamide
    C07888
    N,N-bis(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine 2-oxide
    N,N-bis(2-chloroethyl)-2-oxo-1-oxa-3-aza-2λ5-phosphacyclohexan-2-amine
    (RS)-Cyclophosphamide
    (+-)-Cyclophosphamide
    2-[Bis(2-chloroethylamino)]-tetrahydro-2H-1,3,2-oxazaphosphorine-2-oxide
    50-18-0

Registries:
    PubChem CID 2907
    Beilstein =11744
    CAS 50-18-0 (from NIST)
    ChEBI 4027
    Kegg C07888
    PubChem ID 10090