Zoladex
PubChem Notes:
Goserelin This long-acting GONADORELIN analog and agonist is used in the treatment of malignant NEOPLASMS of the prostate, uterine fibromas, and metastatic breast cancer.
MediLexicon goserelin - Medical Dictionary Definition for Term 'goserelin'
[1. A synthetic decapeptide agonist analogue of LHRH (GnRH). It inhibits pituitary gonadotropin secretion and is used to treat prostate cancer, breast cancer, endometriosis, and for prethinning the endometrium before endometrial ablation or resection.
Molecular Formula:
C59H84N18O14
InChI: InChI=1/C59H84N18O14/c1-31(2)22-40(49(82)68-39(12-8-20-64-57(60)61)56(89)77-21-9-13-46(77)55(88)75-76-58(62)90)69-54(87)45(29-91-59(3,4)5)74-50(83)41(23-32-14-16-35(79)17-15-32)70-53(86)44(28-78)73-51(84)42(24-33-26-65-37-11-7-6-10-36(33)37)71-52(85)43(25-34-27-63-30-66-34)72-48(81)38-18-19-47(80)67-38/h6-7,10-11,14-17,26-27,30-31,38-46,65,78-79H,8-9,12-13,18-25,28-29H2,1-5H3,(H,63,66)(H,67,80)(H,68,82)(H,69,87)(H,70,86)(H,71,85)(H,72,81)(H,73,84)(H,74,83)(H,75,88)(H4,60,61,64)(H3,62,76,90)/f/h66-76H,60-62H2
InChIKey: InChIKey=BLCLNMBMMGCOAS-LMKYEUCVCQ
SMILES: CC(C)CC(C(=O)NC(CCCN=C(N)N)C(=O)N1CCCC1C(=O)NNC(=O)N)NC(=O)C(COC(C)(C)C)NC(=O)C(CC2=CC=C(C=C2)O)NC(=O)C(CO)NC(=O)C(CC3=CNC4=CC=CC=C43)NC(=O)C(CC5=CN=CN5)NC(=O)C6CCC(=O)N6
Names:
Decapeptide I
D-Ser(t-Bu)(sup 6)aza-gly(sup 10)-GNRH
Goserelina [Spanish]
Gosereline [French]
Goserelinum [Latin]
Goserelin acetate
Goserelin [USAN:BAN:INN]
goserelin
ICI 118630
N-[1-[[1-[[1-[[1-[[1-[[1-[[1-[2-[(carbamoylamino)carbamoyl]pyrrolidin-1-yl]-5-(diaminomethylideneamino)-1-oxo-pentan-2-yl]carbamoyl]-3-methyl-butyl]carbamoyl]-2-[(2-methylpropan-2-yl)oxy]ethyl]carbamoyl]-2-(4-hydroxyphenyl)ethyl]carbamoyl]-2-hydroxy-ethyl]carbamoyl]-2-(1H-indol-3-yl)ethyl]carbamoyl]-2-(3H-imidazol-4-yl)ethyl]-5-oxo-pyrrolidine-2-carboxamide
Zoladex
Registries:
PubChem CID 47725
PubChem ID 186963
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