reserpine
PubChem Notes:
Reserpine An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. Reserpine inhibits the uptake of norepinephrine into storage vesicles resulting in depletion of catecholamines and serotonin from central and peripheral axon terminals. It has been used as an antihypertensive and an antipsychotic as well as a research tool, but its adverse effects limit its clinical use.
MediLexicon reserpine - Medical Dictionary Definition for Term 'reserpine'
[1. An ester alkaloid isolated from the root of certain species of Rauwolfia; it decreases the 5-hydroxytryptamine and catecholamine concentrations in the central nervous system and in peripheral tissues; formerly used in conjunction with other agents in the management of essential hypertension and as a tranquilizer in psychotic states.
Molecular Formula:
C33H40N2O9
InChI: InChI=1/C33H40N2O9/c1-38-19-7-8-20-21-9-10-35-16-18-13-27(44-32(36)17-11-25(39-2)30(41-4)26(12-17)40-3)31(42-5)28(33(37)43-6)22(18)15-24(35)29(21)34-23(20)14-19/h7-8,11-12,14,18,22,24,27-28,31,34H,9-10,13,15-16H2,1-6H3/t18-,22+,24-,27-,28+,31+/m1/s1
InChIKey: InChIKey=QEVHRUUCFGRFIF-MDEJGZGSBW
SMILES: COC1C(CC2CN3CCC4=C(C3CC2C1C(=O)OC)NC5=C4C=CC(=C5)OC)OC(=O)C6=CC(=C(C(=C6)OC)OC)OC
Names:
Apoplon
Ascoserpina
Austrapine
Bioserpine
Crystoserpine
Enipresser
Eskaserpine
Helfoserpin
Hiposerpil
reserpine
Registries:
PubChem CID 5770
PubChem ID 107574
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