Pyroglutamic acid

Glp - definition from Biology-Online.org

[5-oxoproline a keto derivative of proline that is formed nonenzymatically from glutamate, glutamine, and gamma-glutamylated peptides; it is also produced by the action of gamma-glutamylcyclotransferase; elevated levels of 5-oxoproline are often associated with problems of glutamine or glutathione metabolism. Synonym: 5-pyrrolidone-2-carboxylic acid, pyroglutamic acid, pyrrolidone-5-carboxylate.

MediLexicon 5-oxoproline - Medical Dictionary Definition for Term '5-oxoproline'

[1. A keto derivative of proline that is formed nonenzymatically from glutamate, glutamine, and γ-glutamylated peptides; it is also produced by the action of γ-glutamylcyclotransferase; elevated levels of 5-oxoproline are often associated with problems of glutamine or glutathione metabolism.

Molecular Formula: C5H7NO3


InChI: InChI=1/C5H7NO3/c7-4-2-1-3(6-4)5(8)9/h3H,1-2H2,(H,6,7)(H,8,9)/f/h6,8H

InChIKey: InChIKey=ODHCTXKNWHHXJC-HJYFZBQUCJ
SMILES: OC(=O)C1CCC(=O)N1

CAS number 149-87-1

Names:
    DL-Proline, 5-oxo-
    DL-Pyroglutamic acid
    Glp
    Pyroglutamate
    Pyroglutamic acid
    2-pyrrolidone-5-carboxylic acid
    5-oxoproline
    5-Oxoproline
    5-OXOPROLINE
    5-oxoproline
    5-oxopyrrolidine-2-carboxylic acid
    5-Pyrrolidone-2-carboxylic acid

Registries:
    PubChem CID 499
    Beilstein =82131
    CAS 149-87-1 (from NIST)
    ChEBI 16010
    chemPDB PCC
    PubChem ID 10364966