Nomifensine maleate
PubChem Notes:
Nomifensine An isoquinoline derivative that prevents dopamine reuptake into synaptosomes. The maleate was formerly used in the treatment of depression. It was withdrawn worldwide in 1986 due to the risk of acute hemolytic anemia with intravascular hemolysis resulting from its use. In some cases, renal failure also developed. (From Martindale, The Extra Pharmacopoeia, 30th ed, p266)
Molecular Formula:
C20H22N2O4
InChI: InChI=1/C16H18N2.C4H4O4/c1-18-10-14(12-6-3-2-4-7-12)13-8-5-9-16(17)15(13)11-18;5-3(6)1-2-4(7)8/h2-9,14H,10-11,17H2,1H3;1-2H,(H,5,6)(H,7,8)/b;2-1-/f/h;5,7H
InChIKey: InChIKey=GEOCVSMCLVIOEV-YQUVJEFBDI
SMILES: CN1CC(C2=C(C1)C(=CC=C2)N)C3=CC=CC=C3.C(=CC(=O)O)C(=O)O
Names:
but-2-enedioic acid; 2-methyl-4-phenyl-3,4-dihydro-1H-isoquinolin-8-amine
HOE 984
Nomifensine hydrogen maleate
Nomifensine maleate
NSC289114
32795-47-4
8-Amino-1,2,3,4-tetrahydro-2-methyl-4-phenylisoquinoline maleate (1:1)
8-Isoquinolinamine, 1,2,3,4-tetrahydro-2-methyl-4-phenyl-, (Z)-2-butenedioate (1:1)
Registries:
PubChem CID 5358907
PubChem ID 144824
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