ZINOSTATIN
PubChem Notes:
Zinostatin An antitumor isolate from the culture filtrate of the F-41 variant of Streptomyces carzinostaticus. It is a protein of known amino acid sequence with a molecular weight of approximately 11,500 and possessing a regulatory function on the metabolism of DNA. In this process, that is first an inhibition of DNA biosynthesis followed by the degradation of DNA, zinostatin functions in a manner analogous to that of the much higher molecular weight antibiotic MITOMYCIN. Zinostatin is also a potent cytostatic agent active against gram-positive organisms.
Molecular Formula:
C35H35NO12
InChI: InChI=1/C35H35NO12/c1-16-12-19(42-4)14-22-20(16)8-9-23(37)27(22)32(40)45-24-13-18-10-11-35(26-15-43-34(41)46-26)25(48-35)7-5-6-21(18)31(24)47-33-28(36-3)30(39)29(38)17(2)44-33/h8-9,12-14,17,21,24-26,28-31,33,36-39H,6,15H2,1-4H3/t17-,21u,24-,25-,26-,28-,29+,30-,31-,33-,35+/m1/s1
InChIKey: InChIKey=BLXZMHNVKCEIJX-JBOXZTMMBG
SMILES: CC1C(C(C(C(O1)OC2C3CC#CC4C(O4)(C#CC3=CC2OC(=O)C5=C(C=CC6=C(C=C(C=C65)OC)C)O)C7COC(=O)O7)NC)O)O
Names:
D02046
Neocarzinostatin (JAN)
Neocarzinostatin
ZINOSTATIN
Zinostatin (USAN)
9014-02-2
Registries:
PubChem CID 5282473
PubChem ID 7849108
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